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Livres
Articles (34)
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The biliary HCO3− umbrella: A unifying hypothesis on pathogenetic and therapeutic aspects of fibrosing cholangiopathies

Ulrich Beuers, Simon Hohenester, Lucas J. Maillette de Buy Wenniger, Andreas E. Kremer, Peter L. M. Jansen, Ronald P. J. Oude Elferink

Journal:

Hepatology

Année:

2010

Langue:

english

Fichier:

PDF, 235 KB

english, 2010

Phosphatidylcholines as regulators of glucose and lipid homeostasis: Promises and potential risks

Simon Hohenester, Ulrich Beuers

Journal:

Hepatology

Année:

2011

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2011

A biliary HCO3− umbrella constitutes a protective mechanism against bile acid-induced injury in human cholangiocytes

Simon Hohenester, Lucas Maillette de Buy Wenniger, Coen C. Paulusma, Sandra J. van Vliet, Douglas M. Jefferson, Ronald P. Oude Elferink, Ulrich Beuers

Journal:

Hepatology

Année:

2012

Langue:

english

Fichier:

PDF, 954 KB

english, 2012

Stepchild phosphohistidine: acid-labile phosphorylation becomes accessible by functional proteomics

Ulli Martin Hohenester, Katrin Ludwig, Josef Krieglstein, Simone König

Journal:

Analytical and Bioanalytical Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 188 KB

english, 2010

Primary biliary cirrhosis

Simon Hohenester, Ronald P. J. Oude-Elferink, Ulrich Beuers

Journal:

Seminars in Immunopathology

Année:

2009

Langue:

english

Fichier:

PDF, 563 KB

english, 2009

Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis

Karin Dilger, Ingolf Cascorbi, Frank Grünhage, Simon Hohenester, Tilman Sauerbruch, Ulrich Beuers

Journal:

Liver International

Année:

2006

Langue:

english

Fichier:

PDF, 132 KB

english, 2006

Phosphatidylinositol-3-kinase p110γ contributes to bile salt-induced apoptosis in primary rat hepatocytes and human hepatoma cells

Simon Hohenester, Anna Gates, Ralf Wimmer, Ulrich Beuers, M. Sawkat Anwer, Christian Rust, Cynthia R.L. Webster

Journal:

Journal of Hepatology

Année:

2010

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2010

Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health

Karin Dilger, Simon Hohenester, Ursula Winkler-Budenhofer, Barbara A.J. Bastiaansen, Frank G. Schaap, Christian Rust, Ulrich Beuers

Journal:

Journal of Hepatology

Année:

2012

Langue:

english

Fichier:

PDF, 977 KB

english, 2012

Role of mitogen-activated protein kinases in tauroursodeoxycholic acid-induced bile formation in cholestatic rat liver

Gerald Ulrich Denk, Simon Hohenester, Ralf Wimmer, Claudia Böhland, Christian Rust, Ulrich Beuers

Journal:

Hepatology Research

Année:

2008

Langue:

english

Fichier:

PDF, 235 KB

english, 2008

Biliary Bicarbonate Secretion Constitutes a Protective Mechanism against Bile Acid- Induced Injury in Man

Hohenester, Simon, Maillette de Buy Wenniger, Lucas, Jefferson, Douglas M., Oude Elferink, Ronald P., Beuers, Ulrich

Journal:

Digestive Diseases

Année:

2011

Langue:

english

Fichier:

PDF, 253 KB

english, 2011

The tumor suppressor annexin A10 is a novel component of nuclear paraspeckles

Quiskamp, Nina, Poeter, Michaela, Raabe, Carsten Alexander, Hohenester, Ulli Martin, KÃ¶nig, Simone, Gerke, Volker, Rescher, Ursula

Journal:

Cellular and Molecular Life Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2014

Antimitochondrial antibodies may be insufficiently specific to define primary biliary cirrhosis-like disease in mouse models

Hohenester, Simon, Beuers, Ulrich, Medina, Juan F., Elferink, Ronald P. Oude

Journal:

Hepatology

Année:

2013

Langue:

english

Fichier:

PDF, 1016 KB

english, 2013

Corrigendum to: “Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health” [J Hepatol 2012;57:133–140]

Dilger, Karin, Hohenester, Simon, Winkler-Budenhofer, Ursula, Bastiaansen, Barbara A.J., Schaap, Frank G., Rust, Christian, Beuers, Ulrich

Journal:

Journal of Hepatology

Année:

2014

Langue:

english

Fichier:

PDF, 254 KB

english, 2014

Fucosyltransferase 2: A Genetic Risk Factor for Primary Sclerosing Cholangitis and Crohn's Disease—A Comprehensive Review

Maroni, Luca, van de Graaf, Stan F. J., Hohenester, Simon D., Oude Elferink, Ronald P. J., Beuers, Ulrich

Journal:

Clinical Reviews in Allergy & Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 395 KB

english, 2015

Soluble intracellular adhesion molecule, M30 and M65 as serum markers of disease activity and prognosis in cholestatic liver diseases

Denk, Gerald, Omary, Ahmed-Jawid, Reiter, Florian Paul, Hohenester, Simon, Wimmer, Ralf, Holdenrieder, Stefan, Rust, Christian

Journal:

Hepatology Research

Année:

2014

Langue:

english

Fichier:

PDF, 737 KB

english, 2014

Physiological hypoxia prevents bile salt-induced apoptosis in human and rat hepatocytes

Hohenester, Simon, Vennegeerts, Timo, Wagner, Michaela, Wimmer, Ralf, Drolle, Heidrun, Rieger, Christina, Denk, Gerald U., Rust, Christian, Fiegl, Michael

Journal:

Liver International

Année:

2014

Langue:

english

Fichier:

PDF, 417 KB

english, 2014

1,25-(OH)2-vitamin D3 prevents activation of hepatic stellate cells in vitro and ameliorates inflammatory liver damage but not fibrosis in the Abcb4−/− model

Reiter, Florian P., Hohenester, Simon, Nagel, Jutta M., Wimmer, Ralf, Artmann, Renate, Wottke, Lena, Makeschin, Marie-Christine, Mayr, Doris, Rust, Christian, Trauner, Michael, Denk, Gerald U.

Journal:

Biochemical and Biophysical Research Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.51 MB

english, 2015

The Cholangiocyte Glycocalyx Stabilizes the �Biliary HCO3- Umbrella': An Integrated Line of Defense against Toxic Bile Acids

Maillette de Buy Wenniger, Lucas J., Hohenester, Simon, Maroni, Luca, van Vliet, Sandra J., Oude Elferink, Ronald P., Beuers, Ulrich

Journal:

Digestive Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 414 KB

english, 2015

Defective bile salt biosynthesis and hydroxylation in mice with reduced cytochrome P450 activity

Kunne, Cindy, Acco, Alexandra, Hohenester, Simon, Duijst, Suzanne, de Waart, Dirk R., Zamanbin, Alaleh, Oude Elferink, Ronald P.J.

Journal:

Hepatology

Année:

2013

Langue:

english

Fichier:

PDF, 711 KB

english, 2013

Knockout of the Primary Sclerosing Cholangitis-Risk Gene Fut2 Causes Liver Disease in Mice

Maroni, Luca, Hohenester, Simon D., van de Graaf, Stan F.J., Tolenaars, Dagmar, van Lienden, Krijn, Verheij, Joanne, Marzioni, Marco, Karlsen, Tom H., Oude Elferink, Ronald P.J., Beuers, Ulrich

Journal:

Hepatology

Année:

2017

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2017

Mitochondrial adaptation in steatotic mice

Einer, Claudia, Hohenester, Simon, Wimmer, Ralf, Wottke, Lena, Artmann, Renate, Schulz, Sabine, Gosmann, Christian, Simmons, Alisha, Leitzinger, Christin, Eberhagen, Carola, Borchard, Sabine, Schmitt,

Journal:

Mitochondrion

Année:

2017

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2017

Data on chow, liver tissue and mitochondrial fatty acid compositions as well as mitochondrial proteome changes after feeding mice a western diet for 6–24 weeks

Journal:

Data in Brief

Année:

2017

Langue:

english

Fichier:

PDF, 174 KB

english, 2017

Lifestyle intervention is effective in treating non-alcoholic fatty liver disease in morbidly obese patients

Hohenester, S., Simon, C., Gerald, D., Gert, B., Rust, C.

Journal:

Journal of Hepatology

Année:

2018

Langue:

english

Fichier:

PDF, 54 KB

english, 2018

Tu1763 - NLRP3-Dependent IL-1β Inhibits Cd103 + Dendritic Cell Differentiation in the Gut

Mak'Anyengo, Rachel, Duewell, Peter, Reichl, Cornelia, Hörth, Christine, Lehr, Hans Anton, Fischer, Sandra, Clavel, Thomas, Denk, Gerald, Hohenester, Simon, Kobold, Sebastian, Endres, Stefan, Schnurr,

Journal:

Gastroenterology

Année:

2018

Langue:

english

Fichier:

PDF, 272 KB

english, 2018

Chemical Phosphorylation of Histidine Residues in Proteins Using Potassium Phosphoramidate – a Tool for the Analysis of Acid-Labile Phosphorylation

Martin Hohenester, Ulli, Ludwig, Katrin, Konig, Simone

Journal:

Current Drug Delivery

Année:

2013

Langue:

english

Fichier:

PDF, 902 KB

english, 2013

Lifestyle intervention for morbid obesity: effects on liver steatosis, inflammation and fibrosis

Hohenester, Simon, Christiansen, Simon, Nagel, Jutta M., Wimmer, Ralf, Artmann, Renate, Denk, Gerald, Bischoff, Monika, Bischoff, Gert, Rust, Christian

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Année:

2018

Langue:

english

Fichier:

PDF, 2.07 MB

english, 2018

Non-invasive assessment of NAFLD as systemic disease—A machine learning perspective

Canbay, Ali, Kälsch, Julia, Neumann, Ursula, Rau, Monika, Hohenester, Simon, Baba, Hideo A., Rust, Christian, Geier, Andreas, Heider, Dominik, Sowa, Jan-Peter, Strnad, Pavel

Journal:

PLoS ONE

Année:

2019

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2019

Predictors of ribociclib-mediated antitumour effects in native and sorafenib-resistant human hepatocellular carcinoma cells

Reiter, Florian P., Denk, Gerald, Ziesch, Andreas, Ofner, Andrea, Wimmer, Ralf, Hohenester, Simon, Schiergens, Tobias S., Spampatti, Matilde, Ye, Liangtao, Itzel, Timo, Munker, Stefan, Teufel, Andreas

Journal:

Cellular Oncology

Année:

2019

Langue:

english

Fichier:

PDF, 2.29 MB

english, 2019

Fatigue in Primary Biliary Cholangitis: no Place for Rituximab

Beuers, Ulrich, Hohenester, Simon

Journal:

Hepatology

Année:

2019

Langue:

english

Fichier:

PDF, 368 KB

english, 2019

Altered Microbiota Diversity and Bile Acid Signaling in Cirrhotic and Noncirrhotic NASH-HCC

Sydor, Svenja, Best, Jan, Messerschmidt, Insa, Manka, Paul, Vilchez-Vargas, Ramiro, Brodesser, Susanne, Lucas, Christina, Wegehaupt, Annemarie, Wenning, Chiara, AÃmuth, Sophia, Hohenester, Simon, Lin

Journal:

Clinical and Translational Gastroenterology

Année:

2020

Fichier:

PDF, 1.00 MB

2020

A disease-specific decline of the relative abundance of Bifidobacterium in patients with autoimmune hepatitis

Liwinski, Timur, Casar, Christian, Ruehlemann, Malte C., Bang, Corinna, Sebode, Marcial, Hohenester, Simon, Denk, Gerald, Lieb, Wolfgang, Lohse, Ansgar W., Franke, Andre, Schramm, Christoph

Journal:

Alimentary Pharmacology & Therapeutics

Année:

2020

Fichier:

PDF, 1.12 MB

2020

Leberzirrhose: Diagnostik und Therapie hÃ¤ufiger Komplikationen

Stecher, Stephanie-Susanne, Hohenester, Simon

Journal:

Intensivmedizin up2date

Année:

2020

Fichier:

PDF, 713 KB

2020

Co-culture of bile-derived organoids from primary sclerosing cholangitis patients with CD4+ T cells replicates pathogenic, CCL20 dependent biliary-immune interactions

Soroka, Carol J., Roberts, Scott, Hohenester, Simon, Boyer, James L., Assis, David N.

Journal:

Journal of Hepatology

Année:

2020

Fichier:

PDF, 141 KB

2020

IL-18 But Not IL-1 Signaling Is Pivotal for the Initiation of Liver Injury in Murine Non-Alcoholic Fatty Liver Disease

Hohenester, Simon, Kanitz, Veronika, Schiergens, Tobias, Einer, Claudia, Nagel, Jutta, Wimmer, Ralf, Reiter, Florian P., Gerbes, Alexander L., De Toni, Enrico N., Bauer, Christian, Holdt, Lesca, Mayr,

Journal:

International Journal of Molecular Sciences

Année:

2020

Fichier:

PDF, 2.22 MB

2020